Using Statistical Techniques and Tools in Clinical Trials

      A epidemiological study can be broadly classified as observational or experimental. Observational studies can be further classified as Descriptive and Analytical. Descriptive studies are usually small clinical observation like case series, case reports which are an effort ...

What role do biomarkers serve in Cancer research and treatment?

      Bio-markers are defined by National cancer institute USA “as a biologic specimen that may be a marker of exposure to a substance, its metabolism, or an integration of exposure and metabolism”.(“Biomarkers,” 2017). In simple words, a biomarker ...

Mass Spectrometry (MS) in Protein biomarker discovery

  Proteomic is the branch which works on the study of proteins and their interactions in human physiology(Carol E. Parker et al., 2010).The field is relatively new field (around 25 years old) but it has established itself as the backbone ...

Personalised medicine: Application of Biomarkers

      The concept of personalized medicine was first promoted when pharmacogenomics data on oncology trials, demonstrated that person’s unique genetic makeup (genome) influences his or her response to medications(“The future of personalized medicine,” n.d.). National cancer institute defines ...

microRNA biomarkers in cancer diagnosis and treatment: Applications in lung cancer

      MicroRNAs (miRNAs) are a class of single stranded, small, endogenous ribonucleic acids (RNAs) of 21–25 nucleotides in length found in both animal and plant cells(Wahid et al., 2010).miRNAs play regulatory roleby targeting specific messenger RNAs (mRNAs) for ...

November 2017
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